Zymeworks (ZYME) Stock: Buy, Sell, or Hold?

ZYME - Zymeworks Inc.

PHARMACEUTICAL PREPARATIONS
$28.44
0.33 (1.16%) ▲
5d: +10.45%
30d: +3.42%
90d: +24.41%
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LOW Confidence
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Analysis Updated: Oct 22, 2026 12:00 AM ET
Earnings: Nov 05, 2026 12d

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Interactive Price Chart (1 Month)

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💡
Bottom Line:
📊 MIXED SIGNALS: ZYME shows conflicting indicators. Wait for confirmation before entering.
See Forward Earnings Fair Value & Price Prediction →

Long-Term Wealth Forecast (2031)

Based on Analyst Consensus Growth & Historical Valuation

0% (Stagnation) 50% (Hyper Growth)
EST. PRICE IN 2031
$21.61
Based on -0.8% avg growth
INTRINSIC VALUE TODAY
$13.42
Trading above historical range

How this is calculated: We use a Growth Decay Model: starting with analyst consensus growth (adjusted above) and gradually slowing it down to a long-term terminal rate (4%) by Year 5. This provides a more realistic valuation than assuming constant hyper-growth. We then apply a 25.0x Exit PE.

In-depth Analysis How we analyze

Valuation Analysis: ZYME is currently trading at $28.44, which is considered extended relative to its 30-day fair value range of $25.43 to $27.17. From a valuation perspective, the stock is trading at a discount (Forward PE: 31.5) compared to its historical average (52.7). Remarkably, the market is currently pricing in an annual earnings decline of 15.7% over the next few years. This aligns with recent fundamental challenges.

Technical Outlook: Technically, ZYME is in a uptrend. The price is approaching resistance at $28.97. A breakout above this level would be a bullish signal, while rejection here could lead to consolidation.

Market Sentiment: ZYME scores 15/100 on our bottoming-setup gauge. Note this measures entry quality, not trend direction — a low score can mean the chart is extended after a strong run (don't chase) or still falling without stabilization; better entries typically come after a pullback toward the 20-day average. Wall Street analysts see significant upside, with an average price target of $41.21 (+44.9%). Current signals suggest waiting for a better entry point before initiating new positions.

Quick Decision Summary

Current Position EXTENDED
Historical Trading Range $25.43 - $27.17
Company Quality Score 35/100 (SELL)
Volume Confirmation HIGH
Confidence Score 28.6%

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All Signals

  • BEARISH: Price extended above range
  • BEARISH: Weak technical setup (15/100)
  • BULLISH: High volume confirmation
  • BULLISH: Trading 44.9% below Wall St target ($41.21)
  • WARNING: Composite score 35/100 in the bottom quintile — this cohort historically lags the market

Trading Range Analysis

30-Day Trading Range $25.43 - $27.17
Current vs Trading Range EXTENDED

Support & Resistance Levels

Support Level $24.60
Resistance Level $28.97
Current Trend Uptrend
Technical data as of Oct 22, 2026

Fundamental Context

Forward P/E (Next Year Est.) 31.51
Wall Street Target $41.21 (+44.9%)
Revenue Growth (YoY) -90.6%
Valuation Discount vs History -15.7% cheaper
PE vs Historical 31.5 vs 52.7 CHEAP
Market-Implied Price Targets If current PE multiple persists
Implied Growth (YoY): -15.7% (market-implied from PE analysis)
1-Year Target $25.60 (-10%)
2-Year Target $23.04 (-19%)
3-Year Target $20.73 (-27%)
3-Yr Target (if PE normalizes) (PE: 32→53) $34.68 (+22%)
3-Year Scenarios Using analyst projected EPS growth
Bull: (PE: 31.5, Growth: -5.6%) $23.94 (+-16%)
Base: (SPY PE: 19.9, Growth: -5.6%) $15.09 (-47%)
Bear: (PE: 16.9, Growth: -5.6%) $12.83 (-55%)
💡 Upside Surprise Potential
If earnings stabilize (0% growth), PE could expand from 31.5 to 52.7
Stabilization Target: $47.57 (+67.3%)
PE Expansion Potential: +67.3%
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Last updated: October 23, 2026 7:42 AM ET
Data refreshes hourly during market hours. Next update: 8:42 AM
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Ticker Score Recommendation Change %
Insider Activity (6 Months)
0
Buys
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Sells
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NEUTRAL

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