ZYME Zymeworks Inc. PHARMACEUTICAL PREPARATIONS Best Pharmaceutical Stocks 2026 →

Zymeworks (ZYME) Stock: Buy, Sell, or Hold?

$27.16
-1.91 (-6.57%) â–ŧ
5d: -5.48% 30d: +9.65% 90d: +8.12%
QUANTITATIVE VERDICT
WAIT
LOW Confidence (45%)
Quality Score
48/100
Position
FAIR
30-Day Fair Range
$25.74 – $29.63
Position: FAIR
Forward P/E & Valuation
23.9x CHEAP
vs 51.0x historical avg
Wall Street Target
$41.93
+44.2% upside
Options IV & Volume
HIGH Vol
HIGH volume confirmation
Support / Resistance
$27.12 / $31.97
Trend: Uptrend
💡Executive Thesis & Bottom Line
Forward Earnings Fair Value & Price Prediction →
â„šī¸ NEUTRAL: ZYME is fairly priced but lacks strong directional signals. At -22.3% expected growth, valuation appears cheap. Wait for clearer setup or better entry on dips.
Smart Money Accumulation

Options open interest is building while the stock consolidates - a pattern consistent with institutional accumulation. View Scanner →

Signal fired Nov 11, 2026 at $29.08 · last confirmed Nov 11, 2026

Strength: 5.5/10

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Interactive Price Chart (1 Month)

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Long-Term Wealth Forecast (2031)

Based on Analyst Consensus Growth & Historical Valuation

0% (Stagnation) 50% (Hyper Growth)
EST. PRICE IN 2031
$37.31
Based on 4.2% avg growth
INTRINSIC VALUE TODAY
$23.16
Trading above historical range

How this is calculated: We use a Growth Decay Model: starting with analyst consensus growth (adjusted above) and gradually slowing it down to a long-term terminal rate (4%) by Year 5. This provides a more realistic valuation than assuming constant hyper-growth. We then apply a 25.0x Exit PE.

In-depth Analysis How we analyze

Valuation Analysis: ZYME is currently trading at $27.16, which is considered fair relative to its 30-day fair value range of $25.74 to $29.63. From a valuation perspective, the stock is trading at a discount (Forward PE: 23.9) compared to its historical average (51.0). Remarkably, the market is currently pricing in an annual earnings decline of 22.3% over the next few years. This aligns with recent fundamental challenges.

Technical Outlook: Technically, ZYME is in a uptrend. The price is currently testing key support at $27.12. A bounce from this level would confirm strength, while a break below could signal further downside. Short-term momentum is weak, with the stock down 6.6% recently.

Market Sentiment: ZYME scores 36/100 on our bottoming-setup gauge. Note this measures entry quality, not trend direction — a low score can mean the chart is extended after a strong run (don't chase) or still falling without stabilization; better entries typically come after a pullback toward the 20-day average. Wall Street analysts see significant upside, with an average price target of $41.93 (+44.2%). Current signals suggest waiting for a better entry point before initiating new positions.

Quick Decision Summary

Current Position FAIR
Historical Trading Range $25.74 - $29.63
Company Quality Score 48/100 (HOLD)
Volume Confirmation HIGH
Confidence Score 45.2%

Trading Range & Key Levels

30-Day Trading Range $25.74 - $29.63
Current vs Trading Range FAIR
Support Level $27.12
Resistance Level $31.97
Current Trend Uptrend
Technical data as of Nov 12, 2026

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Quantitative Signal Breakdown

  • NEUTRAL: Price in fair range
  • BEARISH: Weak technical setup (36/100)
  • BULLISH: High volume confirmation
  • BEARISH: Downward momentum (-6.6%)
  • BULLISH: Trading 44.2% below Wall St target ($41.93)
  • WARNING: Composite score 48/100 in the bottom quintile — this cohort historically lags the market

Fundamental Context

Forward P/E (Next Year Est.) 23.93
Wall Street Target $41.93 (+44.2%)
Revenue Growth (YoY) 828.7%
Profit Margin 16.3%
Valuation Discount vs History -22.3% cheaper
PE vs Historical 23.9 vs 51.0 CHEAP
Market-Implied Price Targets If current PE multiple persists
Implied Growth (YoY): -22.3% (market-implied from PE analysis)
1-Year Target $26.16 (-10%)
2-Year Target $23.55 (-19%)
3-Year Target $21.19 (-27%)
3-Yr Target (if PE normalizes) (PE: 24→51) $45.17 (+55%)
3-Year Scenarios Using analyst projected EPS growth
Bull: (PE: 23.9, Growth: 4.4%) $33.08 (+14%)
Base: (SPY PE: 19.9, Growth: 4.4%) $27.45 (-6%)
Bear: (PE: 16.9, Growth: 4.4%) $23.33 (-20%)
📈 Valuation based on Current Earnings
Forward PE: 21.05 | Forward EPS (Implied): $1.38
Bull Case $35.10 (+21%)
Analyst growth 15.0%, PE expands to 22.1
Base Case $29.07 (0%)
Market implied 0.0%, PE stable at 21.1
Bear Case $22.24 (-24%)
Severe decline -15.0%, PE contracts to 19.0
These are projections based on PE multiples and EPS growth scenarios, not predictions. Actual results may vary significantly.
💡 Upside Surprise Potential
If earnings stabilize (0% growth), PE could expand from 23.9 to 51.0
Stabilization Target: $61.95 (+113.1%)
PE Expansion Potential: +113.1%
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Reddit & Retail Trader Sentiment (ZYME)

Bullish 1 Retail Mentions
StockTwits Volume
1 msgs
24h retail stream
Last Tracked
Nov 11, 2026
Daily AI digest
AI Retail Discussion Summary: StockTwits is currently flooded with bullish sentiment towards $ZYME, with one user expressing frustration towards a perceived 'loser' related to the stock.
Aggregated from r/wallstreetbets, r/stocks & StockTwits streams. View All Trending Reddit & WSB Stocks →
Last updated: November 12, 2026 2:07 PM ET
Data refreshes hourly during market hours. Next update: 3:07 PM
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Ticker Score Recommendation Change %
Insider Activity (6 Months)
0
Buys
0
Sells
0
Net
NEUTRAL

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Part A: Deep-Dive ZYME Research Pages
ZYME Technical Chart ZYME Price Prediction ZYME Intrinsic Value DCF ZYME Earnings Date Why is ZYME Moving Today? ZYME Investment Advisor ZYME Fair Price Analyzer ZYME Options Chain ZYME Options Advisor ZYME Options Analysis ZYME Competitors
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