Alnylam Pharmaceuticals (ALNY) Stock: Buy, Sell, or Hold?

ALNY - Alnylam Pharmaceuticals, Inc.

PHARMACEUTICAL PREPARATIONS
$219.72
-11.46 (-4.96%) β–Ό
5d: -14.16%
30d: -17.83%
90d: -29.81%
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LOW Confidence
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Analysis Updated: Oct 2, 2026 12:00 AM ET
Earnings: Oct 29, 2026 24d

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Interactive Price Chart (1 Month)

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πŸ’‘
Bottom Line:
⏸️ WAIT FOR STABILIZATION: ALNY is down 14.2% over the last 5 days. While fundamentals may be solid, catching a falling knife is risky. Wait for price to stabilize before entering.
See Forward Earnings Fair Value & Price Prediction β†’

Long-Term Wealth Forecast (2031)

Based on Analyst Consensus Growth & Historical Valuation

0% (Stagnation) 50% (Hyper Growth)
EST. PRICE IN 2031
$587.83
Based on 14.5% avg growth
INTRINSIC VALUE TODAY
$365.00
39.8% Margin of Safety

How this is calculated: We use a Growth Decay Model: starting with analyst consensus growth (adjusted above) and gradually slowing it down to a long-term terminal rate (4%) by Year 5. This provides a more realistic valuation than assuming constant hyper-growth. We then apply a 24.3x Exit PE.

In-depth Analysis How we analyze

Valuation Analysis: ALNY is currently trading at $219.72, which is considered oversold relative to its 30-day fair value range of $236.09 to $257.40. From a valuation perspective, the stock is trading at a discount (Forward PE: 17.7) compared to its historical average (24.3). Remarkably, the market is currently pricing in an annual earnings decline of 10.1% over the next few years. This aligns with recent fundamental challenges.

Technical Outlook: Technically, ALNY is in a strong downtrend. The price is currently testing key support at $219.40. A bounce from this level would confirm strength, while a break below could signal further downside. Short-term momentum is weak, with the stock down 5.0% recently.

Market Sentiment: The stock scores a mixed 50/100 on our bottoming-setup gauge, with only partial signs of a stabilized entry point. Wall Street analysts see significant upside, with an average price target of $371.12 (+68.9%). Current signals suggest waiting for a better entry point before initiating new positions.

Quick Decision Summary

Current Position OVERSOLD
Historical Trading Range $236.09 - $257.40
Company Quality Score 49/100 (HOLD)
Volume Confirmation HIGH
Confidence Score 74.8%

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All Signals

  • BULLISH: Price oversold vs 30-day range
  • NEUTRAL: Mixed technical signals (50/100)
  • BULLISH: High volume confirmation
  • BEARISH: Downward momentum (-5.0%)
  • BULLISH: Trading 68.9% below Wall St target ($371.12)
  • WARNING: Composite score 49/100 in the bottom quintile β€” this cohort historically lags the market

Trading Range Analysis

30-Day Trading Range $236.09 - $257.40
Current vs Trading Range OVERSOLD

Support & Resistance Levels

Support Level $219.40
Resistance Level $257.27
Current Trend Strong Downtrend
Technical data as of Oct 2, 2026

Fundamental Context

Forward P/E (Next Year Est.) 17.69
Wall Street Target $371.12 (+68.9%)
Revenue Growth (YoY) 66.9%
Profit Margin 16.1%
Valuation Discount vs History -10.1% cheaper
PE vs Historical 17.7 vs 24.3 CHEAP
Market-Implied Price Targets If current PE multiple persists
Implied Growth (YoY): -10.1% (market-implied from PE analysis)
1-Year Target $197.75 (-10%)
2-Year Target $177.97 (-19%)
3-Year Target $160.18 (-27%)
3-Yr Target (if PE normalizes) (PE: 18β†’24) $220.06 (+0%)
3-Year Scenarios Using analyst projected EPS growth
Bull: (PE: 20.4, Growth: 40.6%) $704.59 (+221%)
Base: (SPY PE: 17.7, Growth: 40.6%) $610.91 (+178%)
Bear: (PE: 15.0, Growth: 40.6%) $519.27 (+136%)
πŸ“ˆ Valuation based on Current Earnings
RECOVERY PLAY: Stock looks expensive now (43x PE), but valuation improves significantly next year (18x PE) as earnings recover.
Trailing PE: 42.89 | Current EPS (TTM): $5.39
Bull Case $508.60 (+132%)
Analyst growth 100.0%, PE expands to 47.2
Base Case $462.36 (+110%)
Market implied 100.0%, PE stable at 42.9
Bear Case $157.20 (-29%)
Severe decline -20.0%, PE contracts to 36.5
These are projections based on PE multiples and EPS growth scenarios, not predictions. Actual results may vary significantly.
πŸ’‘ Upside Surprise Potential
If earnings stabilize (0% growth), PE could expand from 17.7 to 24.3
Stabilization Target: $301.86 (+37.4%)
PE Expansion Potential: +37.4%
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Last updated: October 04, 2026 11:01 AM ET
Data refreshes hourly during market hours. Next update: 12:01 PM
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Ticker Score Recommendation Change %
Insider Activity (6 Months)
0
Buys
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Sells
0
Net
NEUTRAL

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