VRTX Stock Analysis: Buy, Sell, or Hold?

VRTX - Vertex Pharmaceuticals Inc

PHARMACEUTICAL PREPARATIONS
$477.10
-4.60 (-0.95%) ▼
5d: -0.05%
30d: -4.2%
90d: +11.63%
BUY
MODERATE Confidence
Analysis Updated: Jul 31, 2026 12:00 AM ET
Earnings: Aug 03, 2026 0d
Smart Money Distribution

None View Scanner →

Strength: 3.7/10

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Interactive Price Chart (1 Month)

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💡
Bottom Line:
💡 BUY OPPORTUNITY: VRTX shows positive signals but monitor for confirmation. Market pricing in 1.2% annual growth which appears achievable. Moderate conviction.
See Forward Earnings Fair Value & Price Prediction →

Long-Term Wealth Forecast (2031)

Based on Analyst Consensus Growth & Historical Valuation

0% (Stagnation) 50% (Hyper Growth)
EST. PRICE IN 2031
$681.48
Based on 8.2% avg growth
INTRINSIC VALUE TODAY
$423.14
Trading above historical range

How this is calculated: We use a Growth Decay Model: starting with analyst consensus growth (adjusted above) and gradually slowing it down to a long-term terminal rate (4%) by Year 5. This provides a more realistic valuation than assuming constant hyper-growth. We then apply a 21.6x Exit PE.

In-depth Analysis How we analyze

Valuation Analysis: VRTX is currently trading at $477.10, which is considered fair relative to its 30-day fair value range of $471.85 to $504.45. The stock's valuation (Forward PE: 22.4) is in line with its historical norms (21.6). At these levels, the market is pricing in 1.2% annual earnings growth. This growth rate appears achievable given the company's track record, suggesting the valuation is rational.

Technical Outlook: Technically, VRTX is in a strong downtrend. The price is currently testing key support at $465.00. A bounce from this level would confirm strength, while a break below could signal further downside.

Market Sentiment: The stock shows a mixed technical setup (40/100), with neutral trendline and momentum signals. Wall Street analysts see significant upside, with an average price target of $554.91 (+16.3%). Combining these factors, the current setup offers a favorable risk/reward ratio for buyers.

Quick Decision Summary

Current Position FAIR
Historical Trading Range $471.85 - $504.45
Company Quality Score 49/100 (HOLD)
Volume Confirmation HIGH
Confidence Score 71.0%

All Signals

  • NEUTRAL: Price in fair range
  • NEUTRAL: Mixed technical signals (40/100)
  • BULLISH: High volume confirmation
  • BULLISH: Trading below Wall St target ($554.91)
  • NEUTRAL: Market pricing in 1.2% annual earnings growth - fairly valued

Trading Range Analysis

30-Day Trading Range $471.85 - $504.45
Current vs Trading Range FAIR

Support & Resistance Levels

Support Level $465.00
Resistance Level $493.61
Current Trend Strong Downtrend
Technical data as of Jul 31, 2026

Fundamental Context

Forward P/E (Next Year Est.) 22.38
Wall Street Target $554.91 (+16.3%)
Revenue Growth (YoY) 7.8%
Earnings Growth (YoY) 61.4%
Profit Margin 35.5%
Valuation Premium vs History +1.2% premium
PE vs Historical 22.4 vs 21.6 FAIR
Market-Implied Price Targets If current PE multiple persists
Implied Growth (YoY): +1.2% (market-implied from PE analysis)
1-Year Target $482.83 (+1%)
2-Year Target $488.62 (+2%)
3-Year Target $494.48 (+4%)
3-Yr Target (if PE normalizes) (PE: 22→22) PE COMPRESSION $477.17 (0%)
Earnings growth offset by PE compression
3-Year Scenarios Using analyst projected EPS growth
Bull: (PE: 22.4, Growth: 12.4%) $677.48 (+42%)
Base: (SPY PE: 20.7, Growth: 12.4%) $627.43 (+32%)
Bear: (PE: 17.6, Growth: 12.4%) $533.32 (+12%)
📈 Valuation based on Current Earnings
RECOVERY PLAY: Stock looks expensive now (29x PE), but valuation improves significantly next year (22x PE) as earnings recover.
Trailing PE: 28.66 | Current EPS (TTM): $16.81
Bull Case $671.86 (+41%)
Analyst growth 26.8%, PE expands to 31.5
Base Case $610.79 (+28%)
Market implied 26.8%, PE stable at 28.7
Bear Case $327.56 (-31%)
Severe decline -20.0%, PE contracts to 24.4
These are projections based on PE multiples and EPS growth scenarios, not predictions. Actual results may vary significantly.
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Last updated: August 02, 2026 11:50 PM ET
Data refreshes hourly during market hours. Next update: 12:50 AM
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Ticker Score Recommendation Change %
Insider Activity (6 Months)
0
Buys
16
Sells
Net
INSIDERS SELLING
Recent Transactions
Joy Liu SELL 978 shares 2026-04-01
Carmen Bozic SELL 2329 shares 2026-03-13
Amit Sachdev SELL 1846 shares 2026-02-25

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