IONS vs RPRX

Head-to-Head Stock Analysis & Investment Rating

Last Updated: Nov 11, 2026

IONS

49.9
AI Score
VS
IONS Wins

RPRX

36.2
AI Score

Investment Advisor Scores

IONS

50score
Recommendation
HOLD

RPRX

36score
Recommendation
SELL

AI Analyst Insights

AI insights temporarily unavailable

Detailed Metrics Comparison

Metric IONS RPRX Winner
Revenue 756.76M 1.99B RPRX
Net Income -317.14M 457.25M RPRX
Net Margin -41.9% 22.9% RPRX
Operating Income -350.42M 1.11B RPRX
ROE -80.6% 4.7% RPRX
ROA -10.9% 2.3% RPRX
Total Assets 2.91B 19.46B RPRX
Cash 296.30M 513.66M RPRX
Current Ratio 5.43 1.29 IONS

Relative Price Performance (Last 90 Days)

IONS 1M: -33.2% · 3M: -49.3% RPRX 1M: +23.8% · 3M: +19.6%

Current Technical Phase

IONS

Markdown
Sell / avoid

Price below a falling SMA50 (slope -13.9%), weak momentum, RSI 18

RSI (14): 18.1 · Price: $28.33

RPRX

Markup
Hold / add on dips

Price above SMA50, rising 50-day trend (3.6% over 20 days), RSI 79

RSI (14): 79.1 · Price: $70.01

Fundamentals Snapshot

Metric IONS RPRX
Market Cap — —
Forward P/E -22.5 11.8
Trailing P/E — 45.4
Revenue (TTM) — —
Revenue Growth 0.5% 0.1%
Gross Margin 0.0% 1.0%
Operating Margin -0.5% 0.8%
EPS -3.35 1.53
Dividend Yield — 0.01%

Frequently Asked Questions

Based on our detailed analysis, IONS is currently the stronger investment candidate, winning 1 of the key financial metrics based on our comprehensive scoring model.

We analyze revenue and earnings growth rates in the "Growth" section above. Generally, the company with higher year-over-year revenue and EPS growth is fostering better expansion. Check the table above for the specific growth percentages.

Valuation is determined by metrics like the P/E Ratio and PEG Ratio. A lower P/E typically suggests a stock is cheaper relative to its earnings. Refer to the "Valuation" section in our comparison table to see which stock currently trades at a more attractive multiple.