Ionis Pharmaceuticals (IONS) Stock: Buy, Sell, or Hold?
IONS - Ionis Pharmaceuticals, Inc. Common Stock
$43.91
-0.36 (-0.81%)
▼
5d:
-0.48%
30d:
-0.05%
90d:
-22.35%
HOLD
MODERATE Confidence
Analysis Updated: Oct 22, 2026 12:00 AM ET
Earnings: Nov 04, 2026
11d
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Interactive Price Chart (1 Month)
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Bottom Line:
📊 HOLD: IONS shows balanced signals. Fine to hold or accumulate slowly. Monitor for clearer direction.
📊 HOLD: IONS shows balanced signals. Fine to hold or accumulate slowly. Monitor for clearer direction.
In-depth Analysis How we analyze
Valuation Analysis: IONS is currently trading at $43.91, which is considered fair relative to its 30-day fair value range of $42.98 to $46.35.
Technical Outlook: Technically, IONS is in a strong downtrend. Immediate support is located at $42.08, while resistance sits at $45.76.
Market Sentiment: The stock scores a mixed 47/100 on our bottoming-setup gauge, with only partial signs of a stabilized entry point. Wall Street analysts see significant upside, with an average price target of $82.39 (+87.6%). The stock is fairly positioned - fine to hold existing positions or accumulate slowly on dips, but not an urgent buy.
Technical Outlook: Technically, IONS is in a strong downtrend. Immediate support is located at $42.08, while resistance sits at $45.76.
Market Sentiment: The stock scores a mixed 47/100 on our bottoming-setup gauge, with only partial signs of a stabilized entry point. Wall Street analysts see significant upside, with an average price target of $82.39 (+87.6%). The stock is fairly positioned - fine to hold existing positions or accumulate slowly on dips, but not an urgent buy.
Quick Decision Summary
Current Position
FAIR
Historical Trading Range
$42.98 -
$46.35
Company Quality Score
58/100
(HOLD)
Volume Confirmation
HIGH
Confidence Score
74.7%
Protect Your Profits
Holding IONS? Use our AI-powered strategies to protect your downside while keeping your long-term position.
View Profit Protection PlanAll Signals
- NEUTRAL: Price in fair range
- NEUTRAL: Mixed technical signals (47/100)
- BULLISH: High volume confirmation
- BULLISH: Trading 87.6% below Wall St target ($82.39)
- NEUTRAL: Bottoming setup forming (47/100) — watch for confirmation
Trading Range Analysis
30-Day Trading Range
$42.98 -
$46.35
Current vs Trading Range
FAIR
Support & Resistance Levels
Support Level
$42.08
Resistance Level
$45.76
Current Trend
Strong Downtrend
Technical data as of
Oct 22, 2026
Fundamental Context
Forward P/E (Next Year Est.)
-39.48
Wall Street Target
$82.39
(+87.6%)
Revenue Growth (YoY)
-40.7%
Earnings Growth (YoY)
-43.7%
Profit Margin
-64.7%
Share & Embed Analysis
Last updated: October 22, 2026 7:56 PM ET
Data refreshes hourly during market hours. Next update: 8:56 PM
Data refreshes hourly during market hours. Next update: 8:56 PM
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Technical Signals Check
Is IONS showing a specific setup today?
Insider Activity (6 Months)
0
Buys
0
Sells
0
Net
NEUTRAL
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Advanced IONS Option Strategies
Professional options setups generated by AI based on today's IONS price and gamma walls.
