Ionis Pharmaceuticals (IONS) Stock: Buy, Sell, or Hold?
IONS - Ionis Pharmaceuticals, Inc. Common Stock
$54.21
-1.44 (-2.59%)
▼
5d:
-6.74%
30d:
-4.1%
90d:
-26.56%
WAIT
LOW Confidence
Analysis Updated: Sep 11, 2026 12:00 AM ET
Earnings: Nov 04, 2026
Smart Money Accumulation
Options open interest is building while the stock consolidates - a pattern consistent with institutional accumulation. View Scanner →
Signal fired Sep 4, 2026 at $58.09 · last confirmed Sep 9, 2026
Strength: 7.3/10
Get Alerted When IONS Hits Your Target Price
Join 10,000+ traders who never miss a move
You're in! Check your email to confirm and set your target price.
100% Free
No spam, ever
Unsubscribe anytime
Interactive Price Chart (1 Month)
Loading chart...
Loading historical data...
Bottom Line:
📊 MIXED SIGNALS: IONS shows conflicting indicators. Wait for confirmation before entering.
📊 MIXED SIGNALS: IONS shows conflicting indicators. Wait for confirmation before entering.
In-depth Analysis How we analyze
Valuation Analysis: IONS is currently trading at $54.21, which is considered oversold relative to its 30-day fair value range of $55.37 to $60.99.
Technical Outlook: Technically, IONS is in a strong uptrend. Immediate support is located at $52.15, while resistance sits at $61.77.
Market Sentiment: IONS scores 25/100 on our bottoming-setup gauge. Note this measures entry quality, not trend direction — a low score can mean the chart is extended after a strong run (don't chase) or still falling without stabilization; better entries typically come after a pullback toward the 20-day average. Wall Street analysts see significant upside, with an average price target of $84.23 (+55.4%). Current signals suggest waiting for a better entry point before initiating new positions.
Technical Outlook: Technically, IONS is in a strong uptrend. Immediate support is located at $52.15, while resistance sits at $61.77.
Market Sentiment: IONS scores 25/100 on our bottoming-setup gauge. Note this measures entry quality, not trend direction — a low score can mean the chart is extended after a strong run (don't chase) or still falling without stabilization; better entries typically come after a pullback toward the 20-day average. Wall Street analysts see significant upside, with an average price target of $84.23 (+55.4%). Current signals suggest waiting for a better entry point before initiating new positions.
Quick Decision Summary
Current Position
OVERSOLD
Historical Trading Range
$55.37 -
$60.99
Company Quality Score
50/100
(HOLD)
Volume Confirmation
HIGH
Confidence Score
57.9%
Protect Your Profits
Holding IONS? Use our AI-powered strategies to protect your downside while keeping your long-term position.
View Profit Protection PlanAll Signals
- BULLISH: Price oversold vs 30-day range
- BEARISH: Weak technical setup (25/100)
- BULLISH: High volume confirmation
- BULLISH: Trading 55.4% below Wall St target ($84.23)
- WARNING: Composite score 50/100 in the bottom quintile — this cohort historically lags the market
Trading Range Analysis
30-Day Trading Range
$55.37 -
$60.99
Current vs Trading Range
OVERSOLD
Support & Resistance Levels
Support Level
$52.15
Resistance Level
$61.77
Current Trend
Strong Uptrend
Technical data as of
Sep 11, 2026
Fundamental Context
Forward P/E (Next Year Est.)
-48.74
Wall Street Target
$84.23
(+55.4%)
Revenue Growth (YoY)
-40.7%
Earnings Growth (YoY)
-43.7%
Profit Margin
-64.7%
Share & Embed Analysis
Last updated: September 12, 2026 8:24 AM ET
Data refreshes hourly during market hours. Next update: 9:24 AM
Data refreshes hourly during market hours. Next update: 9:24 AM
🔥 Top Stocks Breaking Out Now
| Ticker | Score | Recommendation | Change % |
|---|
Technical Signals Check
Is IONS showing a specific setup today?
Insider Activity (6 Months)
0
Buys
6
Sells
Net
INSIDERS SELLING
Recent Transactions
Kyle Jenne
SELL
4902 shares
2026-04-16
Brian Birchler
SELL
973 shares
2026-04-16
B Lynne Parshall
SELL
5000 shares
2026-04-15
Top Rated Biotechnology Stocks
Top-rated stocks in Biotechnology by analyst ratings.
| Stock | Analyst Consensus | Analyst Target | Tradestie Score |
|---|---|---|---|
|
LEGN
Legend Biotech Corp |
STRONG BUY
22 analysts |
$49 | 44 HOLD |
|
ARGX
argenx NV ADR |
STRONG BUY
22 analysts |
$1180 | 43 HOLD |
|
SRPT
Sarepta Therapeutics Inc |
STRONG BUY
26 analysts |
$22 | 34 SELL |
|
KYMR
Kymera Therapeutics Inc |
STRONG BUY
20 analysts |
$135 | 47 HOLD |
|
MRUS
Merus BV |
STRONG BUY
17 analysts |
$97 | 39 SELL |
Advanced IONS Option Strategies
Professional options setups generated by AI based on today's IONS price and gamma walls.
