Ionis Pharmaceuticals (IONS) Stock: Buy, Sell, or Hold?
IONS - Ionis Pharmaceuticals, Inc. Common Stock
$43.45
-0.55 (-1.25%)
▼
5d:
-2.36%
30d:
-29.15%
90d:
-47.76%
HOLD
LOW Confidence
Analysis Updated: Oct 2, 2026 12:00 AM ET
Earnings: Nov 04, 2026
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Interactive Price Chart (1 Month)
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Bottom Line:
📊 HOLD: IONS shows balanced signals. Fine to hold or accumulate slowly. Monitor for clearer direction.
📊 HOLD: IONS shows balanced signals. Fine to hold or accumulate slowly. Monitor for clearer direction.
In-depth Analysis How we analyze
Valuation Analysis: IONS is currently trading at $43.45, which is considered oversold relative to its 30-day fair value range of $44.76 to $59.66.
Technical Outlook: Technically, IONS is in a strong uptrend. The price is currently testing key support at $43.01. A bounce from this level would confirm strength, while a break below could signal further downside.
Market Sentiment: IONS scores 74/100 on our bottoming-setup gauge — the chart has corrected and is stabilizing (RSI reset, momentum turning up), historically a favorable entry zone. Wall Street analysts see significant upside, with an average price target of $83.64 (+90.1%). The stock is fairly positioned - fine to hold existing positions or accumulate slowly on dips, but not an urgent buy.
Technical Outlook: Technically, IONS is in a strong uptrend. The price is currently testing key support at $43.01. A bounce from this level would confirm strength, while a break below could signal further downside.
Market Sentiment: IONS scores 74/100 on our bottoming-setup gauge — the chart has corrected and is stabilizing (RSI reset, momentum turning up), historically a favorable entry zone. Wall Street analysts see significant upside, with an average price target of $83.64 (+90.1%). The stock is fairly positioned - fine to hold existing positions or accumulate slowly on dips, but not an urgent buy.
Quick Decision Summary
Current Position
OVERSOLD
Historical Trading Range
$44.76 -
$59.66
Company Quality Score
71/100
(BUY)
Volume Confirmation
HIGH
Confidence Score
94.7%
Protect Your Profits
Holding IONS? Use our AI-powered strategies to protect your downside while keeping your long-term position.
View Profit Protection PlanAll Signals
- BULLISH: Price oversold vs 30-day range
- BULLISH: Strong technical setup (74/100)
- BULLISH: High volume confirmation
- BULLISH: Trading 90.1% below Wall St target ($83.64)
- CAUTION: Bottoming setup, but lagging the sector by 40% over 20 days — wait for relative strength
Trading Range Analysis
30-Day Trading Range
$44.76 -
$59.66
Current vs Trading Range
OVERSOLD
Support & Resistance Levels
Support Level
$43.01
Resistance Level
$46.95
Current Trend
Strong Uptrend
Technical data as of
Oct 2, 2026
Fundamental Context
Forward P/E (Next Year Est.)
-39.56
Wall Street Target
$83.64
(+90.1%)
Revenue Growth (YoY)
-40.7%
Earnings Growth (YoY)
-43.7%
Profit Margin
-64.7%
Share & Embed Analysis
Last updated: October 02, 2026 1:32 PM ET
Data refreshes hourly during market hours. Next update: 2:32 PM
Data refreshes hourly during market hours. Next update: 2:32 PM
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Technical Signals Check
Is IONS showing a specific setup today?
Insider Activity (6 Months)
0
Buys
3
Sells
Net
INSIDERS SELLING
Recent Transactions
Kyle Jenne
SELL
4902 shares
2026-04-16
Brian Birchler
SELL
973 shares
2026-04-16
B Lynne Parshall
SELL
5000 shares
2026-04-15
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Advanced IONS Option Strategies
Professional options setups generated by AI based on today's IONS price and gamma walls.
