IONS Stock Analysis: Buy, Sell, or Hold?
IONS - Ionis Pharmaceuticals, Inc. Common Stock
$76.77
0.88 (1.15%)
▲
5d:
+3.79%
30d:
+1.3%
90d:
+8.44%
BUY
MODERATE Confidence
Analysis Updated: Jun 22, 2026 12:00 AM ET
Earnings: Jul 29, 2026
Smart Money Accumulation
None View Scanner →
Strength: 8.0/10
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Interactive Price Chart (1 Month)
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Bottom Line:
💡 BUY OPPORTUNITY: IONS shows positive signals but monitor for confirmation. Company currently unprofitable (negative forward earnings). Moderate conviction.
💡 BUY OPPORTUNITY: IONS shows positive signals but monitor for confirmation. Company currently unprofitable (negative forward earnings). Moderate conviction.
In-depth Analysis How we analyze
Valuation Analysis: IONS is currently trading at $76.77, which is considered extended relative to its 30-day fair value range of $73.41 to $75.88.
Technical Outlook: Technically, IONS is in a strong uptrend. The price is approaching resistance at $76.32. A breakout above this level would be a bullish signal, while rejection here could lead to consolidation.
Market Sentiment: IONS has a strong technical setup (60/100), with favorable trendlines, momentum, and price action for short-term traders. Wall Street analysts see significant upside, with an average price target of $104.91 (+38.2%). Combining these factors, the current setup offers a favorable risk/reward ratio for buyers.
Technical Outlook: Technically, IONS is in a strong uptrend. The price is approaching resistance at $76.32. A breakout above this level would be a bullish signal, while rejection here could lead to consolidation.
Market Sentiment: IONS has a strong technical setup (60/100), with favorable trendlines, momentum, and price action for short-term traders. Wall Street analysts see significant upside, with an average price target of $104.91 (+38.2%). Combining these factors, the current setup offers a favorable risk/reward ratio for buyers.
Quick Decision Summary
Current Position
EXTENDED
Historical Trading Range
$73.41 -
$75.88
Company Quality Score
66/100
(BUY)
Volume Confirmation
HIGH
Confidence Score
63.2%
All Signals
- BEARISH: Price extended above range
- BULLISH: Strong technical setup (60/100)
- BULLISH: High volume confirmation
- BULLISH: Trading 38.2% below Wall St target ($104.91)
Trading Range Analysis
30-Day Trading Range
$73.41 -
$75.88
Current vs Trading Range
EXTENDED
Support & Resistance Levels
Support Level
$72.30
Resistance Level
$76.32
Current Trend
Strong Uptrend
Technical data as of
Jun 22, 2026
Fundamental Context
Forward P/E (Next Year Est.)
-102.03
Wall Street Target
$104.91
(+38.2%)
Revenue Growth (YoY)
87.0%
Earnings Growth (YoY)
-43.7%
Profit Margin
-30.9%
Share & Embed Analysis
Last updated: June 23, 2026 10:10 AM ET
Data refreshes hourly during market hours. Next update: 11:10 AM
Data refreshes hourly during market hours. Next update: 11:10 AM
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Technical Signals Check
Is IONS showing a specific setup today?
Insider Activity (6 Months)
0
Buys
20
Sells
Net
INSIDERS SELLING
Recent Transactions
Kyle Jenne
SELL
4902 shares
2026-04-16
Brian Birchler
SELL
973 shares
2026-04-16
B Lynne Parshall
SELL
5000 shares
2026-04-15
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