IONS Stock Analysis: Buy, Sell, or Hold?
IONS - Ionis Pharmaceuticals, Inc. Common Stock
$57.24
1.37 (2.45%)
â˛
5d:
+1.2%
30d:
+4.74%
90d:
-24.37%
WAIT
LOW Confidence
Analysis Updated: Aug 14, 2026 12:00 AM ET
Earnings: Jul 29, 2026
0d
Smart Money Accumulation
Options open interest is building while the stock consolidates - a pattern consistent with institutional accumulation. View Scanner →
Signal fired Aug 7, 2026 at $56.56 · last confirmed Aug 11, 2026
Strength: 7.4/10
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Interactive Price Chart (1 Month)
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Bottom Line:
âšī¸ NEUTRAL: IONS is fairly priced but lacks strong directional signals. Wait for clearer setup or better entry on dips.
âšī¸ NEUTRAL: IONS is fairly priced but lacks strong directional signals. Wait for clearer setup or better entry on dips.
In-depth Analysis How we analyze
Valuation Analysis: IONS is currently trading at $57.24, which is considered fair relative to its 30-day fair value range of $49.38 to $67.41.
Technical Outlook: Technically, IONS is in a strong uptrend. The price is approaching resistance at $57.66. A breakout above this level would be a bullish signal, while rejection here could lead to consolidation.
Market Sentiment: IONS scores 30/100 on our bottoming-setup gauge. Note this measures entry quality, not trend direction — a low score can mean the chart is extended after a strong run (don't chase) or still falling without stabilization; better entries typically come after a pullback toward the 20-day average. Wall Street analysts see significant upside, with an average price target of $89.33 (+56.1%). Current signals suggest waiting for a better entry point before initiating new positions.
Technical Outlook: Technically, IONS is in a strong uptrend. The price is approaching resistance at $57.66. A breakout above this level would be a bullish signal, while rejection here could lead to consolidation.
Market Sentiment: IONS scores 30/100 on our bottoming-setup gauge. Note this measures entry quality, not trend direction — a low score can mean the chart is extended after a strong run (don't chase) or still falling without stabilization; better entries typically come after a pullback toward the 20-day average. Wall Street analysts see significant upside, with an average price target of $89.33 (+56.1%). Current signals suggest waiting for a better entry point before initiating new positions.
Quick Decision Summary
Current Position
FAIR
Historical Trading Range
$49.38 -
$67.41
Company Quality Score
50/100
(HOLD)
Volume Confirmation
HIGH
Confidence Score
50.0%
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Holding IONS? Use our AI-powered strategies to protect your downside while keeping your long-term position.
View Profit Protection PlanAll Signals
- NEUTRAL: Price in fair range
- BEARISH: Weak technical setup (30/100)
- BULLISH: High volume confirmation
- BULLISH: Trading 56.1% below Wall St target ($89.33)
- WARNING: Composite score 50/100 in the bottom quintile â this cohort historically lags the market
Trading Range Analysis
30-Day Trading Range
$49.38 -
$67.41
Current vs Trading Range
FAIR
Support & Resistance Levels
Support Level
$52.17
Resistance Level
$57.66
Current Trend
Strong Uptrend
Technical data as of
Aug 14, 2026
Fundamental Context
Forward P/E (Next Year Est.)
-49.34
Wall Street Target
$89.33
(+56.1%)
Revenue Growth (YoY)
-40.7%
Earnings Growth (YoY)
-43.7%
Profit Margin
-64.7%
Share & Embed Analysis
Last updated: August 16, 2026 3:06 AM ET
Data refreshes hourly during market hours. Next update: 4:06 AM
Data refreshes hourly during market hours. Next update: 4:06 AM
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Technical Signals Check
Is IONS showing a specific setup today?
Insider Activity (6 Months)
0
Buys
14
Sells
Net
INSIDERS SELLING
Recent Transactions
Kyle Jenne
SELL
4902 shares
2026-04-16
Brian Birchler
SELL
973 shares
2026-04-16
B Lynne Parshall
SELL
5000 shares
2026-04-15
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Advanced IONS Option Strategies
Professional options setups generated by AI based on today's IONS price and gamma walls.
