ISRG vs VRTX

Head-to-Head Stock Analysis & Investment Rating

Last Updated: Sep 27, 2026

ISRG

32.0
AI Score
VS
VRTX Wins

VRTX

52.9
AI Score

Investment Advisor Scores

ISRG

32score
Recommendation
AVOID NEW MONEY

VRTX

53score
Recommendation
HOLD

AI Analyst Insights

Detailed Metrics Comparison

Metric ISRG VRTX Winner
Forward P/E 33.3333 24.0964 VRTX
PEG Ratio 1.8715 1.8976 ISRG
Revenue Growth 18.5% 12.5% ISRG
Earnings Growth 26.5% 8.0% ISRG
Tradestie Score 32.0/100 52.9/100 VRTX
Profit Margin 28.4% 35.0% VRTX
Beta 1.00 1.00 Tie
AI Recommendation AVOID NEW MONEY HOLD VRTX

Relative Price Performance (Last 90 Days)

ISRG 1M: +5.4% · 3M: -9.4% VRTX 1M: -9.3% · 3M: -4.7%

Current Technical Phase

ISRG

Neutral
Hold

Mixed signals - no dominant trend phase, RSI 51

RSI (14): 51.3 · Price: $391.95

VRTX

Neutral
Hold

Mixed signals - no dominant trend phase, RSI 39

RSI (14): 39.1 · Price: $504.73

Fundamentals Snapshot

Metric ISRG VRTX
Market Cap — —
Forward P/E 32.4 25.1
Trailing P/E 46.7 29.7
Revenue (TTM) — —
Revenue Growth 0.2% 0.1%
Gross Margin 0.7% 0.5%
Operating Margin 0.3% 0.4%
EPS 8.59 17.04
Dividend Yield — —

Frequently Asked Questions

Based on our detailed analysis, VRTX is currently the stronger investment candidate based on our comprehensive scoring model.

We analyze revenue and earnings growth rates in the "Growth" section above. Generally, the company with higher year-over-year revenue and EPS growth is fostering better expansion. Check the table above for the specific growth percentages.

Valuation is determined by metrics like the P/E Ratio and PEG Ratio. A lower P/E typically suggests a stock is cheaper relative to its earnings. Refer to the "Valuation" section in our comparison table to see which stock currently trades at a more attractive multiple.