ISRG vs VRTX

Head-to-Head Stock Analysis & Investment Rating

Last Updated: Aug 01, 2026

ISRG

46.6
AI Score
VS
VRTX Wins

VRTX

48.8
AI Score

Investment Advisor Scores

ISRG

47score
Recommendation
HOLD

VRTX

49score
Recommendation
HOLD

AI Analyst Insights

Detailed Metrics Comparison

Metric ISRG VRTX Winner
Forward P/E 32.7869 25.0627 VRTX
PEG Ratio 1.7323 1.6385 VRTX
Revenue Growth 18.5% 7.8% ISRG
Earnings Growth 26.5% 61.4% VRTX
Tradestie Score 46.6/100 48.8/100 VRTX
Profit Margin 28.4% 35.5% VRTX
Beta 1.00 1.00 Tie
AI Recommendation HOLD HOLD Tie

Relative Price Performance (Last 90 Days)

ISRG 1M: -12.2% · 3M: -22.8% VRTX 1M: -4.2% · 3M: +11.6%

Current Technical Phase

ISRG

Markdown
Sell / avoid

Price below a falling SMA50 (slope -7.1%), weak momentum, RSI 40

RSI (14): 39.8 · Price: $353.33

VRTX

Neutral
Hold

Mixed signals - no dominant trend phase, RSI 48

RSI (14): 48.2 · Price: $477.10

Fundamentals Snapshot

Metric ISRG VRTX
Market Cap
Forward P/E 29.3 22.4
Trailing P/E 40.5 28.7
Revenue (TTM)
Revenue Growth 0.2% 0.1%
Gross Margin 0.7% 0.5%
Operating Margin 0.3% 0.4%
EPS 8.72 16.81
Dividend Yield

Frequently Asked Questions

Based on our detailed analysis, VRTX is currently the stronger investment candidate based on our comprehensive scoring model.

We analyze revenue and earnings growth rates in the "Growth" section above. Generally, the company with higher year-over-year revenue and EPS growth is fostering better expansion. Check the table above for the specific growth percentages.

Valuation is determined by metrics like the P/E Ratio and PEG Ratio. A lower P/E typically suggests a stock is cheaper relative to its earnings. Refer to the "Valuation" section in our comparison table to see which stock currently trades at a more attractive multiple.