Karyopharm Therapeutics (KPTI) Stock: Buy, Sell, or Hold?

KPTI - Karyopharm Therapeutics Inc.

PHARMACEUTICAL PREPARATIONS
$0.80
-0.06 (-7.45%) β–Ό
5d: -50.48%
30d: -55.18%
90d: -91.66%
WAIT
LOW Confidence
Analysis Updated: Oct 2, 2026 12:00 AM ET
Earnings: Nov 02, 2026 29d

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Interactive Price Chart (1 Month)

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πŸ’‘
Bottom Line:
⏸️ WAIT FOR STABILIZATION: KPTI is down 50.5% over the last 5 days. While fundamentals may be solid, catching a falling knife is risky. Wait for price to stabilize before entering.
See Forward Earnings Fair Value & Price Prediction β†’

In-depth Analysis How we analyze

Valuation Analysis: KPTI is currently trading at $0.80, which is considered oversold relative to its 30-day fair value range of $1.38 to $1.96.

Technical Outlook: Technically, KPTI is in a strong downtrend. Immediate support is located at $0.75, while resistance sits at $1.93. Short-term momentum is weak, with the stock down 7.5% recently.

Market Sentiment: KPTI scores 25/100 on our bottoming-setup gauge. Note this measures entry quality, not trend direction — a low score can mean the chart is extended after a strong run (don't chase) or still falling without stabilization; better entries typically come after a pullback toward the 20-day average. Wall Street analysts see significant upside, with an average price target of $7.25 (+803.8%). Current signals suggest waiting for a better entry point before initiating new positions.

Quick Decision Summary

Current Position OVERSOLD
Historical Trading Range $1.38 - $1.96
Company Quality Score 42/100 (HOLD)
Volume Confirmation HIGH
Confidence Score 52.6%

All Signals

  • BULLISH: Price oversold vs 30-day range
  • BEARISH: Weak technical setup (25/100)
  • BULLISH: High volume confirmation
  • BEARISH: Downward momentum (-7.5%)
  • BULLISH: Trading 803.8% below Wall St target ($7.25)
  • WARNING: Composite score 42/100 in the bottom quintile β€” this cohort historically lags the market

Trading Range Analysis

30-Day Trading Range $1.38 - $1.96
Current vs Trading Range OVERSOLD

Support & Resistance Levels

Support Level $0.75
Resistance Level $1.93
Current Trend Strong Downtrend
Technical data as of Oct 2, 2026

Fundamental Context

Forward P/E (Next Year Est.) -0.28
Wall Street Target $7.25 (+803.8%)
Revenue Growth (YoY) -11.9%
Profit Margin -153.3%
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Last updated: October 03, 2026 6:57 AM ET
Data refreshes hourly during market hours. Next update: 7:57 AM
πŸ”₯ Top Stocks Breaking Out Now
Ticker Score Recommendation Change %
Technical Signals Check
Insider Activity (6 Months)
0
Buys
1
Sells
Net
INSIDERS SELLING
Recent Transactions
Reshma Rangwala SELL 449 shares 2026-04-21

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