LYEL Lyell Immunopharma, Inc. Common Stock PHARMACEUTICAL PREPARATIONS Best Pharmaceutical Stocks 2026 →

Lyell Immunopharma (LYEL) Stock: Buy, Sell, or Hold?

$15.64
-1.22 (-7.24%) β–Ό
5d: +4.27% 30d: +95.74% 90d: +12.11%
QUANTITATIVE VERDICT
WAIT
LOW Confidence (23%)
Quality Score
33/100
Position
EXTENDED
30-Day Fair Range
$7.94 – $13.77
Position: EXTENDED
Forward P/E & Valuation
-2.5x
Next 12M consensus est.
Wall Street Target
$38.38
+145.4% upside
Options IV & Volume
38th pct IV
HIGH volume confirmation
Support / Resistance
$10.56 / $17.61
Trend: Downtrend
πŸ’‘Executive Thesis & Bottom Line
Forward Earnings Fair Value & Price Prediction →
⏸️ WAIT FOR BETTER ENTRY: LYEL is 13.6% above its trading range ($13.77). While momentum could continue, risk/reward favors waiting for a pullback.

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Interactive Price Chart (1 Month)

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In-depth Analysis How we analyze

Valuation Analysis: LYEL is currently trading at $15.64, which is considered extended relative to its 30-day fair value range of $7.94 to $13.77.

Technical Outlook: Technically, LYEL is in a downtrend. Immediate support is located at $10.56, while resistance sits at $17.61. Short-term momentum is weak, with the stock down 7.2% recently.

Market Sentiment: LYEL scores 0/100 on our bottoming-setup gauge. Note this measures entry quality, not trend direction — a low score can mean the chart is extended after a strong run (don't chase) or still falling without stabilization; better entries typically come after a pullback toward the 20-day average. Wall Street analysts see significant upside, with an average price target of $38.38 (+145.4%). Current signals suggest waiting for a better entry point before initiating new positions.

Quick Decision Summary

Current Position EXTENDED
Historical Trading Range $7.94 - $13.77
Company Quality Score 33/100 (SELL)
Options IV Signal 38th percentile (NORMAL)
Volume Confirmation HIGH
Confidence Score 22.9%

Trading Range & Key Levels

30-Day Trading Range $7.94 - $13.77
Current vs Trading Range EXTENDED
Expected Move (7 Days) Β±$3.80 (24.3%)
Support Level $10.56
Resistance Level $17.61
Current Trend Downtrend
Technical data as of Nov 12, 2026

Quantitative Signal Breakdown

  • BEARISH: Price significantly overextended (+13.6% above its trading range)
  • NEUTRAL: Options fairly priced (IV 38th percentile)
  • BEARISH: Weak technical setup (0/100)
  • BULLISH: High volume confirmation
  • BEARISH: Downward momentum (-7.2%)
  • BULLISH: Trading 145.4% below Wall St target ($38.38)
  • WARNING: Composite score 33/100 in the bottom quintile β€” this cohort historically lags the market

Fundamental Context

Forward P/E (Next Year Est.) -2.47
Wall Street Target $38.38 (+145.4%)
Revenue Growth (YoY) -80.0%
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Reddit & Retail Trader Sentiment (LYEL)

Bullish 1 Retail Mentions
StockTwits Volume
1 msgs
24h retail stream
Last Tracked
Nov 4, 2026
Daily AI digest
AI Retail Discussion Summary: StockTwits shows bullish sentiment towards $LYEL with the message 'LYEL Flowing' being shared by a bullish trader with 11746 followers.
Key Retail Themes: bullish sentiment
Aggregated from r/wallstreetbets, r/stocks & StockTwits streams. View All Trending Reddit & WSB Stocks →
Last updated: November 12, 2026 9:36 PM ET
Data refreshes hourly during market hours. Next update: 10:36 PM
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Ticker Score Recommendation Change %
Technical Signals Check
Insider Activity (6 Months)
0
Buys
0
Sells
0
Net
NEUTRAL

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Part A: Deep-Dive LYEL Research Pages
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