Spero Therapeutics (SPRO) Stock: Buy, Sell, or Hold?

SPRO - Spero Therapeutics, Inc. Common Stock

PHARMACEUTICAL PREPARATIONS
$1.11
-0.02 (-1.77%) ▼
5d: +0.91%
30d: -11.2%
90d: -5.93%
WAIT
LOW Confidence
Analysis Updated: Oct 23, 2026 12:00 AM ET
Earnings: Nov 12, 2026 18d

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Interactive Price Chart (1 Month)

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💡
Bottom Line:
📊 MIXED SIGNALS: SPRO shows conflicting indicators. Wait for confirmation before entering.
See Forward Earnings Fair Value & Price Prediction →

In-depth Analysis How we analyze

Valuation Analysis: SPRO is currently trading at $1.11, which is considered oversold relative to its 30-day fair value range of $1.12 to $1.23. From a valuation perspective, the stock is trading at a discount (Forward PE: -10.6) compared to its historical average (6.5). At these levels, the market is pricing in 0% annual earnings growth. This growth rate appears achievable given the company's track record, suggesting the valuation is rational.

Technical Outlook: Technically, SPRO is in a strong downtrend. The price is currently testing key support at $1.09. A bounce from this level would confirm strength, while a break below could signal further downside.

Market Sentiment: The stock scores a mixed 40/100 on our bottoming-setup gauge, with only partial signs of a stabilized entry point. Implied Volatility is high (100th percentile), indicating expensive options premiums. This environment often favors selling options or covered calls to generate income. Wall Street analysts see significant upside, with an average price target of $5.00 (+350.5%). Current signals suggest waiting for a better entry point before initiating new positions.

Quick Decision Summary

Current Position OVERSOLD
Historical Trading Range $1.12 - $1.23
Company Quality Score 43/100 (HOLD)
Options IV Signal 100th percentile (EVENT RISK)
Volume Confirmation HIGH
Confidence Score 68.1%

All Signals

  • BULLISH: Price oversold vs 30-day range
  • BEARISH: Options expensive (IV 100th percentile)
  • NEUTRAL: Mixed technical signals (40/100)
  • BULLISH: High volume confirmation
  • BULLISH: Trading 350.5% below Wall St target ($5.00)
  • BULLISH: Market expects only 0% annual growth - appears undervalued
  • WARNING: Composite score 43/100 in the bottom quintile — this cohort historically lags the market

Trading Range Analysis

30-Day Trading Range $1.12 - $1.23
Current vs Trading Range OVERSOLD
Expected Move (7 Days) ±$0.60 (54.2%)

Support & Resistance Levels

Support Level $1.09
Resistance Level $1.24
Current Trend Strong Downtrend
Technical data as of Oct 23, 2026

Fundamental Context

Forward P/E (Next Year Est.) -10.57
Wall Street Target $5.00 (+350.5%)
Revenue Growth (YoY) -95.6%
Earnings Growth (YoY) 75.3%
Profit Margin 15.7%
PE vs Historical -10.6 vs 6.5 CHEAP
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Last updated: October 23, 2026 8:07 PM ET
Data refreshes hourly during market hours. Next update: 9:07 PM
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Ticker Score Recommendation Change %
Technical Signals Check
Insider Activity (6 Months)
0
Buys
0
Sells
0
Net
NEUTRAL

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