Spero Therapeutics (SPRO) Stock: Buy, Sell, or Hold?
SPRO - Spero Therapeutics, Inc. Common Stock
$1.19
-0.07 (-5.56%)
âŧ
5d:
-3.25%
30d:
-2.46%
90d:
-45.66%
WAIT
LOW Confidence
Analysis Updated: Oct 2, 2026 12:00 AM ET
Earnings: Nov 12, 2026
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Interactive Price Chart (1 Month)
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Bottom Line:
âšī¸ NEUTRAL: SPRO is fairly priced but lacks strong directional signals. At 0% expected growth, valuation appears cheap. Wait for clearer setup or better entry on dips.
âšī¸ NEUTRAL: SPRO is fairly priced but lacks strong directional signals. At 0% expected growth, valuation appears cheap. Wait for clearer setup or better entry on dips.
In-depth Analysis How we analyze
Valuation Analysis: SPRO is currently trading at $1.19, which is considered fair relative to its 30-day fair value range of $1.14 to $1.25. From a valuation perspective, the stock is trading at a discount (Forward PE: -11.3) compared to its historical average (6.5). At these levels, the market is pricing in 0% annual earnings growth. This growth rate appears achievable given the company's track record, suggesting the valuation is rational.
Technical Outlook: Technically, SPRO is in a strong downtrend. Immediate support is located at $1.12, while resistance sits at $1.44. Short-term momentum is weak, with the stock down 5.6% recently.
Market Sentiment: SPRO scores 30/100 on our bottoming-setup gauge. Note this measures entry quality, not trend direction — a low score can mean the chart is extended after a strong run (don't chase) or still falling without stabilization; better entries typically come after a pullback toward the 20-day average. Wall Street analysts see significant upside, with an average price target of $5.00 (+320.2%). Current signals suggest waiting for a better entry point before initiating new positions.
Technical Outlook: Technically, SPRO is in a strong downtrend. Immediate support is located at $1.12, while resistance sits at $1.44. Short-term momentum is weak, with the stock down 5.6% recently.
Market Sentiment: SPRO scores 30/100 on our bottoming-setup gauge. Note this measures entry quality, not trend direction — a low score can mean the chart is extended after a strong run (don't chase) or still falling without stabilization; better entries typically come after a pullback toward the 20-day average. Wall Street analysts see significant upside, with an average price target of $5.00 (+320.2%). Current signals suggest waiting for a better entry point before initiating new positions.
Quick Decision Summary
Current Position
FAIR
Historical Trading Range
$1.14 -
$1.25
Company Quality Score
39/100
(SELL)
Options IV Signal
55th percentile
(NORMAL)
Volume Confirmation
HIGH
Confidence Score
53.8%
All Signals
- NEUTRAL: Price in fair range
- NEUTRAL: Options fairly priced (IV 55th percentile)
- BEARISH: Weak technical setup (30/100)
- BULLISH: High volume confirmation
- BEARISH: Downward momentum (-5.6%)
- BULLISH: Trading 320.2% below Wall St target ($5.00)
- BULLISH: Market expects only 0% annual growth - appears undervalued
- WARNING: Composite score 39/100 in the bottom quintile â this cohort historically lags the market
Trading Range Analysis
30-Day Trading Range
$1.14 -
$1.25
Current vs Trading Range
FAIR
Expected Move (7 Days)
Âą$0.34
(28.2%)
Support & Resistance Levels
Support Level
$1.12
Resistance Level
$1.44
Current Trend
Strong Downtrend
Technical data as of
Oct 2, 2026
Fundamental Context
Forward P/E (Next Year Est.)
-11.33
Wall Street Target
$5.00
(+320.2%)
Revenue Growth (YoY)
-95.6%
Earnings Growth (YoY)
75.3%
Profit Margin
15.7%
PE vs Historical
-11.3 vs 6.5
CHEAP
Share & Embed Analysis
Last updated: October 02, 2026 7:40 PM ET
Data refreshes hourly during market hours. Next update: 8:40 PM
Data refreshes hourly during market hours. Next update: 8:40 PM
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Technical Signals Check
Is SPRO showing a specific setup today?
Insider Activity (6 Months)
0
Buys
0
Sells
0
Net
NEUTRAL
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