ISRG vs VRTX

Head-to-Head Stock Analysis & Investment Rating

Last Updated: Aug 22, 2026

ISRG

45.7
AI Score
VS
ISRG Wins

VRTX

29.5
AI Score

Investment Advisor Scores

ISRG

46score
Recommendation
HOLD

VRTX

30score
Recommendation
EXTENDED

AI Analyst Insights

Detailed Metrics Comparison

Metric ISRG VRTX Winner
Forward P/E 36.9004 27.7008 VRTX
PEG Ratio 1.9503 1.8103 VRTX
Revenue Growth 18.5% 12.5% ISRG
Earnings Growth 26.5% 8.0% ISRG
Tradestie Score 45.7/100 29.5/100 ISRG
Profit Margin 28.4% 35.0% VRTX
Beta 1.00 1.00 Tie
AI Recommendation HOLD EXTENDED Tie

Relative Price Performance (Last 90 Days)

ISRG 1M: +14.1% · 3M: -13.9% VRTX 1M: +15.8% · 3M: +26.4%

Current Technical Phase

ISRG

Distribution
Trim / tighten stop

Price near a flattening SMA50 (slope -4.6%) with fading momentum, RSI 48

RSI (14): 47.6 · Price: $378.81

VRTX

Markup
Hold / add on dips

Price above SMA50, rising 50-day trend (5.7% over 20 days), RSI 67

RSI (14): 67.0 · Price: $548.05

Fundamentals Snapshot

Metric ISRG VRTX
Market Cap
Forward P/E 31.4 24.8
Trailing P/E 43.0 30.8
Revenue (TTM)
Revenue Growth 0.2% 0.1%
Gross Margin 0.7% 0.5%
Operating Margin 0.3% 0.4%
EPS 8.71 17.94
Dividend Yield

Frequently Asked Questions

Based on our detailed analysis, ISRG is currently the stronger investment candidate based on our comprehensive scoring model.

We analyze revenue and earnings growth rates in the "Growth" section above. Generally, the company with higher year-over-year revenue and EPS growth is fostering better expansion. Check the table above for the specific growth percentages.

Valuation is determined by metrics like the P/E Ratio and PEG Ratio. A lower P/E typically suggests a stock is cheaper relative to its earnings. Refer to the "Valuation" section in our comparison table to see which stock currently trades at a more attractive multiple.