IONS Stock Analysis: Buy, Sell, or Hold?
IONS - Ionis Pharmaceuticals, Inc. Common Stock
$62.04
2.30 (3.85%)
▲
5d:
+5.82%
30d:
+9.71%
90d:
-17.89%
WAIT
LOW Confidence
Analysis Updated: Aug 24, 2026 12:00 AM ET
Earnings: Jul 29, 2026
0d
Smart Money Distribution
Options positioning is turning defensive after a sharp run-up - a pattern consistent with institutional profit-taking. View Scanner →
Signal fired Aug 24, 2026 at $62.04 · last confirmed Aug 24, 2026
Strength: 6.6/10
Get Alerted When IONS Hits Your Target Price
Join 10,000+ traders who never miss a move
You're in! Check your email to confirm and set your target price.
100% Free
No spam, ever
Unsubscribe anytime
Interactive Price Chart (1 Month)
Loading chart...
Loading historical data...
Bottom Line:
📊 MIXED SIGNALS: IONS shows conflicting indicators. Wait for confirmation before entering.
📊 MIXED SIGNALS: IONS shows conflicting indicators. Wait for confirmation before entering.
In-depth Analysis How we analyze
Valuation Analysis: IONS is currently trading at $62.04, which is considered extended relative to its 30-day fair value range of $53.57 to $58.47.
Technical Outlook: Technically, IONS is in a strong uptrend. The price is approaching resistance at $62.07. A breakout above this level would be a bullish signal, while rejection here could lead to consolidation. The stock is showing strong short-term momentum, up 3.9% recently.
Market Sentiment: IONS scores 13/100 on our bottoming-setup gauge. Note this measures entry quality, not trend direction — a low score can mean the chart is extended after a strong run (don't chase) or still falling without stabilization; better entries typically come after a pullback toward the 20-day average. Wall Street analysts see significant upside, with an average price target of $88.00 (+41.8%). Current signals suggest waiting for a better entry point before initiating new positions.
Technical Outlook: Technically, IONS is in a strong uptrend. The price is approaching resistance at $62.07. A breakout above this level would be a bullish signal, while rejection here could lead to consolidation. The stock is showing strong short-term momentum, up 3.9% recently.
Market Sentiment: IONS scores 13/100 on our bottoming-setup gauge. Note this measures entry quality, not trend direction — a low score can mean the chart is extended after a strong run (don't chase) or still falling without stabilization; better entries typically come after a pullback toward the 20-day average. Wall Street analysts see significant upside, with an average price target of $88.00 (+41.8%). Current signals suggest waiting for a better entry point before initiating new positions.
Quick Decision Summary
Current Position
EXTENDED
Historical Trading Range
$53.57 -
$58.47
Company Quality Score
37/100
(SELL)
Volume Confirmation
HIGH
Confidence Score
26.3%
Protect Your Profits
Holding IONS? Use our AI-powered strategies to protect your downside while keeping your long-term position.
View Profit Protection PlanAll Signals
- BEARISH: Price extended above range (+6.1% above its trading range)
- BEARISH: Weak technical setup (13/100)
- BULLISH: High volume confirmation
- BULLISH: Strong upward momentum (+3.9%)
- BULLISH: Trading 41.8% below Wall St target ($88.00)
- WARNING: Composite score 37/100 in the bottom quintile — this cohort historically lags the market
Trading Range Analysis
30-Day Trading Range
$53.57 -
$58.47
Current vs Trading Range
EXTENDED
Support & Resistance Levels
Support Level
$54.91
Resistance Level
$62.07
Current Trend
Strong Uptrend
Technical data as of
Aug 24, 2026
Fundamental Context
Forward P/E (Next Year Est.)
-58.83
Wall Street Target
$88.00
(+41.8%)
Revenue Growth (YoY)
-40.7%
Earnings Growth (YoY)
-43.7%
Profit Margin
-64.7%
Share & Embed Analysis
Last updated: August 24, 2026 11:01 PM ET
Data refreshes hourly during market hours. Next update: 12:01 AM
Data refreshes hourly during market hours. Next update: 12:01 AM
🔥 Top Stocks Breaking Out Now
| Ticker | Score | Recommendation | Change % |
|---|
Technical Signals Check
Is IONS showing a specific setup today?
Insider Activity (6 Months)
0
Buys
14
Sells
Net
INSIDERS SELLING
Recent Transactions
Kyle Jenne
SELL
4902 shares
2026-04-16
Brian Birchler
SELL
973 shares
2026-04-16
B Lynne Parshall
SELL
5000 shares
2026-04-15
Top Rated Biotechnology Stocks
Top-rated stocks in Biotechnology by analyst ratings.
| Stock | Analyst Consensus | Analyst Target | Tradestie Score |
|---|---|---|---|
|
NTLA
Intellia Therapeutics Inc |
STRONG BUY
29 analysts |
$24 | 39 SELL |
|
REGN
Regeneron Pharmaceutical… |
STRONG BUY
25 analysts |
$840 | 40 SELL |
|
JAZZ
Jazz Pharmaceuticals PLC |
STRONG BUY
18 analysts |
$281 | 62 BUY |
|
ARGX
argenx NV ADR |
STRONG BUY
22 analysts |
$1173 | 33 SELL |
|
MLTX
MoonLake Immunotherapeut… |
STRONG BUY
16 analysts |
$29 | 48 HOLD |
Advanced IONS Option Strategies
Professional options setups generated by AI based on today's IONS price and gamma walls.
