SYRE
Spyre Therapeutics, Inc. Common Stock
PHARMACEUTICAL PREPARATIONS
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Spyre Therapeutics (SYRE) Stock: Buy, Sell, or Hold?
$106.82
+2.34 (+2.24%)
▲
5d:
+7.86%
30d:
+32.78%
90d:
+4.88%
QUANTITATIVE VERDICT
WAIT
LOW Confidence (18%)
Quality Score
33/100
Position
EXTENDED
30-Day Fair Range
$83.06 – $101.06
Position: EXTENDED
Forward P/E & Valuation
-28.9x
Next 12M consensus est.
Wall Street Target
$122.67
+14.8% upside
Options IV & Volume
HIGH Vol
HIGH volume confirmation
Support / Resistance
$92.77 / $110.64
Trend: Sideways
Executive Thesis & Bottom Line
Forward Earnings Fair Value & Price Prediction →
📊 MIXED SIGNALS: SYRE shows conflicting indicators. Wait for confirmation before entering.
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Interactive Price Chart (1 Month)
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In-depth Analysis How we analyze
Valuation Analysis: SYRE is currently trading at $106.82, which is considered extended relative to its 30-day fair value range of $83.06 to $101.06.
Technical Outlook: Technically, SYRE is showing sideways momentum. Immediate support is located at $92.77, while resistance sits at $110.64.
Market Sentiment: SYRE scores 6/100 on our bottoming-setup gauge. Note this measures entry quality, not trend direction — a low score can mean the chart is extended after a strong run (don't chase) or still falling without stabilization; better entries typically come after a pullback toward the 20-day average. Wall Street analysts see significant upside, with an average price target of $122.67 (+14.8%). Current signals suggest waiting for a better entry point before initiating new positions.
Technical Outlook: Technically, SYRE is showing sideways momentum. Immediate support is located at $92.77, while resistance sits at $110.64.
Market Sentiment: SYRE scores 6/100 on our bottoming-setup gauge. Note this measures entry quality, not trend direction — a low score can mean the chart is extended after a strong run (don't chase) or still falling without stabilization; better entries typically come after a pullback toward the 20-day average. Wall Street analysts see significant upside, with an average price target of $122.67 (+14.8%). Current signals suggest waiting for a better entry point before initiating new positions.
Quick Decision Summary
Current Position
EXTENDED
Historical Trading Range
$83.06 -
$101.06
Company Quality Score
33/100
(SELL)
Volume Confirmation
HIGH
Confidence Score
18.4%
Trading Range & Key Levels
30-Day Trading Range
$83.06 -
$101.06
Current vs Trading Range
EXTENDED
Support Level
$92.77
Resistance Level
$110.64
Current Trend
Sideways
Technical data as of
Nov 11, 2026
Quantitative Signal Breakdown
- BEARISH: Price extended above range (+5.7% above its trading range)
- BEARISH: Weak technical setup (6/100)
- BULLISH: High volume confirmation
- BULLISH: Trading below Wall St target ($122.67)
- WARNING: Composite score 33/100 in the bottom quintile — this cohort historically lags the market
Fundamental Context
Forward P/E (Next Year Est.)
-28.93
Wall Street Target
$122.67
(+14.8%)
Earnings Growth (YoY)
-99.7%
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bloggers & journalists: you are free to use our charts with attribution.Reddit & Retail Trader Sentiment (SYRE)
Bullish
1 Retail Mentions
StockTwits Volume
1 msgs
24h retail stream
Last Tracked
Nov 6, 2026
Daily AI digest
AI Retail Discussion Summary:
StockTwits messages suggest a bullish outlook for $SYRE, with no recent Yahoo Finance news available.
Key Retail Themes:
bullish sentiment
Aggregated from r/wallstreetbets, r/stocks & StockTwits streams.
View All Trending Reddit & WSB Stocks →
Last updated: November 11, 2026 7:10 PM ET
Data refreshes hourly during market hours. Next update: 8:10 PM
Data refreshes hourly during market hours. Next update: 8:10 PM
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Technical Signals Check
Is SYRE showing a specific setup today?
Insider Activity (6 Months)
0
Buys
0
Sells
0
Net
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