IONS Stock Analysis: Buy, Sell, or Hold?
IONS - Ionis Pharmaceuticals, Inc. Common Stock
$59.74
0.98 (1.67%)
▲
5d:
+4.37%
30d:
+6.93%
90d:
-21.17%
WAIT
LOW Confidence
Analysis Updated: Aug 21, 2026 12:00 AM ET
Earnings: Jul 29, 2026
0d
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Interactive Price Chart (1 Month)
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Bottom Line:
📊 MIXED SIGNALS: IONS shows conflicting indicators. Wait for confirmation before entering.
📊 MIXED SIGNALS: IONS shows conflicting indicators. Wait for confirmation before entering.
In-depth Analysis How we analyze
Valuation Analysis: IONS is currently trading at $59.74, which is considered extended relative to its 30-day fair value range of $53.66 to $57.87.
Technical Outlook: Technically, IONS is in a strong uptrend. The price is approaching resistance at $61.35. A breakout above this level would be a bullish signal, while rejection here could lead to consolidation.
Market Sentiment: IONS scores 20/100 on our bottoming-setup gauge. Note this measures entry quality, not trend direction — a low score can mean the chart is extended after a strong run (don't chase) or still falling without stabilization; better entries typically come after a pullback toward the 20-day average. Wall Street analysts see significant upside, with an average price target of $88.00 (+47.3%). Current signals suggest waiting for a better entry point before initiating new positions.
Technical Outlook: Technically, IONS is in a strong uptrend. The price is approaching resistance at $61.35. A breakout above this level would be a bullish signal, while rejection here could lead to consolidation.
Market Sentiment: IONS scores 20/100 on our bottoming-setup gauge. Note this measures entry quality, not trend direction — a low score can mean the chart is extended after a strong run (don't chase) or still falling without stabilization; better entries typically come after a pullback toward the 20-day average. Wall Street analysts see significant upside, with an average price target of $88.00 (+47.3%). Current signals suggest waiting for a better entry point before initiating new positions.
Quick Decision Summary
Current Position
EXTENDED
Historical Trading Range
$53.66 -
$57.87
Company Quality Score
40/100
(SELL)
Volume Confirmation
HIGH
Confidence Score
26.3%
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View Profit Protection PlanAll Signals
- BEARISH: Price extended above range
- BEARISH: Weak technical setup (20/100)
- BULLISH: High volume confirmation
- BULLISH: Trading 47.3% below Wall St target ($88.00)
- WARNING: Composite score 40/100 in the bottom quintile — this cohort historically lags the market
Trading Range Analysis
30-Day Trading Range
$53.66 -
$57.87
Current vs Trading Range
EXTENDED
Support & Resistance Levels
Support Level
$54.91
Resistance Level
$61.36
Current Trend
Strong Uptrend
Technical data as of
Aug 21, 2026
Fundamental Context
Forward P/E (Next Year Est.)
-56.65
Wall Street Target
$88.00
(+47.3%)
Revenue Growth (YoY)
-40.7%
Earnings Growth (YoY)
-43.7%
Profit Margin
-64.7%
Share & Embed Analysis
Last updated: August 23, 2026 12:21 AM ET
Data refreshes hourly during market hours. Next update: 1:21 AM
Data refreshes hourly during market hours. Next update: 1:21 AM
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Technical Signals Check
Is IONS showing a specific setup today?
Insider Activity (6 Months)
0
Buys
14
Sells
Net
INSIDERS SELLING
Recent Transactions
Kyle Jenne
SELL
4902 shares
2026-04-16
Brian Birchler
SELL
973 shares
2026-04-16
B Lynne Parshall
SELL
5000 shares
2026-04-15
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Advanced IONS Option Strategies
Professional options setups generated by AI based on today's IONS price and gamma walls.
