IONS
Ionis Pharmaceuticals, Inc. Common Stock
PHARMACEUTICAL PREPARATIONS
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Ionis Pharmaceuticals (IONS) Stock: Buy, Sell, or Hold?
$28.33
+0.14 (+0.50%)
▲
5d:
-29.44%
30d:
-33.15%
90d:
-49.29%
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Earnings: Nov 09, 2026
0d
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Updated Nov 11, 12:00 AM ET
QUANTITATIVE VERDICT
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LOW Confidence (58%)
Quality Score
50/100
Position
OVERSOLD
30-Day Fair Range
$36.97 – $46.22
Position: OVERSOLD
Forward P/E & Valuation
-22.5x
Next 12M consensus est.
Wall Street Target
$76.96
+171.6% upside
Options IV & Volume
HIGH Vol
HIGH volume confirmation
Support / Resistance
$27.75 / $45.84
Trend: Strong Uptrend
Executive Thesis & Bottom Line
Forward Earnings Fair Value & Price Prediction →
⏸️ WAIT FOR STABILIZATION: IONS is down 29.4% over the last 5 days. While fundamentals may be solid, catching a falling knife is risky. Wait for price to stabilize before entering.
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Interactive Price Chart (1 Month)
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In-depth Analysis How we analyze
Valuation Analysis: IONS is currently trading at $28.33, which is considered oversold relative to its 30-day fair value range of $36.97 to $46.22.
Technical Outlook: Technically, IONS is in a strong uptrend. The price is currently testing key support at $27.75. A bounce from this level would confirm strength, while a break below could signal further downside.
Market Sentiment: IONS scores 35/100 on our bottoming-setup gauge. Note this measures entry quality, not trend direction — a low score can mean the chart is extended after a strong run (don't chase) or still falling without stabilization; better entries typically come after a pullback toward the 20-day average. Wall Street analysts see significant upside, with an average price target of $76.96 (+171.6%). Current signals suggest waiting for a better entry point before initiating new positions.
Technical Outlook: Technically, IONS is in a strong uptrend. The price is currently testing key support at $27.75. A bounce from this level would confirm strength, while a break below could signal further downside.
Market Sentiment: IONS scores 35/100 on our bottoming-setup gauge. Note this measures entry quality, not trend direction — a low score can mean the chart is extended after a strong run (don't chase) or still falling without stabilization; better entries typically come after a pullback toward the 20-day average. Wall Street analysts see significant upside, with an average price target of $76.96 (+171.6%). Current signals suggest waiting for a better entry point before initiating new positions.
Quick Decision Summary
Current Position
OVERSOLD
Historical Trading Range
$36.97 -
$46.22
Company Quality Score
50/100
(HOLD)
Volume Confirmation
HIGH
Confidence Score
57.9%
Trading Range & Key Levels
30-Day Trading Range
$36.97 -
$46.22
Current vs Trading Range
OVERSOLD
Support Level
$27.75
Resistance Level
$45.84
Current Trend
Strong Uptrend
Technical data as of
Nov 11, 2026
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View Profit Protection PlanQuantitative Signal Breakdown
- BULLISH: Price oversold vs 30-day range
- BEARISH: Weak technical setup (35/100)
- BULLISH: High volume confirmation
- BULLISH: Trading 171.6% below Wall St target ($76.96)
- WARNING: Composite score 50/100 in the bottom quintile — this cohort historically lags the market
Fundamental Context
Forward P/E (Next Year Est.)
-22.46
Wall Street Target
$76.96
(+171.6%)
Revenue Growth (YoY)
54.9%
Earnings Growth (YoY)
-43.7%
Profit Margin
-56.9%
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bloggers & journalists: you are free to use our charts with attribution.Reddit & Retail Trader Sentiment (IONS)
Bullish
2 Retail Mentions
Reddit / WSB Comments
1
Bearish
StockTwits Volume
1 msgs
24h retail stream
Last Tracked
Nov 10, 2026
Daily AI digest
AI Retail Discussion Summary:
Ionis Pharmaceuticals reported Q3 2026 revenue of $243 million, reaffirmed full year revenue guidance, and narrowed quarterly net loss. The stock received a price target adjustment from Oppenheimer.
Key Retail Themes:
revenue beat and reaffirmed outlook
price target adjustment
Aggregated from r/wallstreetbets, r/stocks & StockTwits streams.
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Last updated: November 11, 2026 7:10 PM ET
Data refreshes hourly during market hours. Next update: 8:10 PM
Data refreshes hourly during market hours. Next update: 8:10 PM
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Technical Signals Check
Is IONS showing a specific setup today?
Insider Activity (6 Months)
0
Buys
0
Sells
0
Net
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Part A: Deep-Dive IONS Research Pages
